CAPSULATION OF PNEUMOCOCCUS WITH SOLUBLE CELL WALL-LIKE POLYSACCHARIDE
نویسندگان
چکیده
منابع مشابه
Capsulation of Pneumococcus with Soluble Cell Wall-like Polysaccharide
Methods are described for the separation of the C or cell wall polysaccharide from the C(s) or soluble C-like capsular polysaccharide of C(s) pneumococcal strains. Immunologic analysis has shown that both the C and C(s) polysaccharides of a variety of pneumococcal strains are heterogeneous and that the dissimilarities appear to reside in the mucopeptide portion of the molecule or in the region ...
متن کاملCAPSULATION OF PNEUMOCOCCUS WITH SOLUBLE C-LIKE (Cs) POLYSACCHARIDE
Capsulated mutants of pneumococcus producing a capsule of soluble polysaccharide related immunologically to the C or cell wall polysaccharide of pneumococcus have been isolated from several noncapsulated variants of this organism. The capsular material of these strains reacts with antisera both to homologous strains and to noncapsulated strains of pneumococcus and with human C-reactive protein....
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The capsular polysaccharide of Type IX pneumococcus contains D-glucose, N-acetyl-D-glucosamine, and D-glucuronic acid. Complete hydrolysis is difficult. All of the N-acetylglucosamine is resistant to oxidation by periodate, but the other two sugars are degraded in part. Chemical and quantitative serological data are consistent with the linkage of two D-glucose residues 1 --> 4, as in maltose; o...
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Peptidoglycan (PG)-polysaccharide (PS) polymers derived from group A streptococcal cell walls were solubilized by M-1 mutanolysin (endo-N-acetylmuramidase) and phage-associated lysin (N-acetylmuramyl-l-alanine amidase). Fragments were isolated by ultrafiltration and a series of gel filtrations and were injected intravenously into Sprague-Dawley rats. No fragments with a molecular weight of less...
متن کاملThe Complement Fixation Reaction with Pneumococcus Capsular Polysaccharide
1. Complement is not fixed by immune aggregates resulting from the interaction of pneumococcus capsular polysaccharide and type-specific immune horse serum, although under proper conditions the substitution of immune rabbit serum gives positive results. 2. The negative results with immune horse serum are due to some poorly understood property of the specific antibodies rather than to some heter...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1971
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.134.3.600